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Sulfasalazine induced agranulocytosis treated with granulocyte-macrophage colony stimulating factor
E J Kuipers1, E Vellenga, J T de Wolf
1Department of Internal Medicine, University Hospital, Groningen, The Netherlands.
The Journal of Rheumatology
|April 1, 1992
Abstract:
We report the use of granulocyte-macrophage colony stimulating factor (GM-CSF) in a case of rheumatoid arthritis with sulfasalazine induced agranulocytosis, leading to a rapid bone marrow recovery within 7 days. This case and 2 others reported in the literature emphasize the need for further research into the possible role of GM-CSF in the treatment of drug induced agranulocytosis.