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[Comparative study on lymphocyte stimulation by PHA and bacterial endotoxins, particularly in malignant tumor and
Abstract:
In a group of 37 tumor patients with predominantly advanced disease, LPS stimulation (LPS of Sh. sonnei and Sh. flexneri) resulted in a significant increase of the transformation rates caused, most probably, by the high proportion of B cells. On the other hand, allergics (drug allergies) did not differ from controls. It seems possible that B cell stimulation by bacterial endotoxins can be used for the assessment of the reactivity of the organism.