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Antihistaminic activity of quinethindole: a 2-substituted pyrazinopyridoindole derivative
G K Patnaik1, A K Saxena, M Saxena
1Central Drug Research Institute, Lucknow, India.
Indian Journal of Experimental Biology
|February 1, 1992
Abstract:
Quinethindole, a 2-substituted pyrazinopyridoindole, showed specific antihistaminic (H1) activity in various in vivo and in vitro test models. It also inhibited antigen-induced contraction of ileum of sensitized guinea pig. The antihistaminic activity was of competitive nature.