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Possible induction of intercellular adhesion molecule-1 (ICAM-1) expression on endothelial cells by
J Chihara1, I Maruyama, H Yasuba
1Fourth Department of Internal Medicine, Kinki University School of Medicine, Osaka, Japan.
Journal of Lipid Mediators
|June 1, 1992
Abstract:
We demonstrated that PAF and IL-1 markedly induce ICAM-1 expression on endothelial cells. These findings suggest that PAF not only modulates inflammation by the attraction and activation of eosinophils or by platelet activation, but also intensifies such phenomena by induction of ICAM-1 expression on endothelial cells.