Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Abnormal premovement brain potentials in schizophrenia.

J Singh1, R T Knight, N Rosenlicht

  • 1Department of Psychology, Northwestern University.

Schizophrenia Research
|October 1, 1992
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Yield Loss Assessment in Canola: Effects of Brown Girdling Root Rot and Maggot Damage on Single Plant Yield.

Plant disease·2019
Same author

Addressing poor maternal and fetal outcomes.

South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde·2012
Same author

Intermodal attention modulates visual processing in dorsal and ventral streams.

NeuroImage·2012
Same author

Efficacy of tailored computer-based neurorehabilitation for improvement of movement initiation in Parkinson's disease.

Brain research·2012
Same author

Selective cerebral hypothermia for post-hypoxic neuroprotection in neonates using a solid ice cap.

South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde·2006
Same author

Escalation/de-escalation patterns of behavioral symptoms of persons with dementia.

Aging & mental health·2004
Same journal

Quality evaluation of randomized controlled trials of antipsychotic drugs for schizophrenia published in Chinese journals.

Schizophrenia research·2026
Same journal

FL-SDGIN: A federated graph learning approach for schizophrenia diagnosis integrating static and dynamic brain functional networks.

Schizophrenia research·2026
Same journal

Weight loss and gut microbial changes associated with semaglutide among people living with schizophrenia receiving clozapine or olanzapine: An open-label 24-week semaglutide intervention and 76-week trial.

Schizophrenia research·2026
Same journal

Converting negative symptom dimension scores across SANS and PANSS.

Schizophrenia research·2026
Same journal

Inflammation-associated alterations in mGluR transcript expression in the human nucleus accumbens independent of schizophrenia diagnosis.

Schizophrenia research·2026
Same journal

One social interaction after another: Dynamic modeling of social experience in schizophrenia.

Schizophrenia research·2026
See all related articles

Schizophrenia patients show impaired voluntary movement preparation. Their movement-related potentials (MRPs) were reduced, suggesting frontal lobe dysfunction, similar to patients with prefrontal cortex lesions.

Area of Science:

  • Neuroscience
  • Psychiatry

Background:

  • Schizophrenia is a complex psychiatric disorder associated with cognitive deficits.
  • Movement-related potentials (MRPs) reflect voluntary motor preparation.

Purpose of the Study:

  • To investigate preparatory motor processes in schizophrenia using MRPs.
  • To compare MRPs in medicated schizophrenic patients and healthy controls.

Main Methods:

  • Scalp-recorded MRPs were assessed during a self-paced button press task.
  • Nine medicated schizophrenic patients and nine age-matched controls participated.

Main Results:

  • Healthy controls exhibited a readiness potential (RP), negative shift (NS'), and motor potential (MP).
  • Schizophrenic patients showed reduced initial MRP components (RP and NS').

Related Experiment Videos

Conclusions:

  • Schizophrenia is associated with impaired voluntary preparatory processes.
  • Findings suggest frontal lobe dysfunction in schizophrenia, similar to dorsolateral prefrontal cortex lesions.