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Updated: Jul 27, 2026
Metabolic Analysis of Drosophila melanogaster Larval and Adult Brains
Published on: August 7, 2018
Monoamines and their metabolites in the amphibian (Ambystoma tigrinum) brain: quantitative changes during
D O Norris1, J A Carr, P H Desan
1Department of Environmental, Population and Organismic Biology, University of Colorado, Boulder 80309-0334.
Abstract:
1. Monoamine neurotransmitters (epinephrine, norepinephrine, dopamine, serotonin and some of their metabolites (DOPEG, MHPG, DOPAC, 5-HIAA) were measured by HPLC in extracts from telencephalon (TEL) and diencephalon-midbrain (DM) before, during at the end of metamorphosis. 2. During metamorphosis MHPG increased and 5-HIAA decreased in TEL and DM while DOPEG decreased only in DM. 3. Monoamine levels were greater in the TEL and a larger increase in MHPG occurred there. 4. Captivity without metamorphosis also caused a significant depression of 5-HIAA in TEL and depression of DOPEG, MHPG and DOPAC in DM.
