Enhanced peritoneal dialysis delivery with PD-PLUS

We prospectively studied the effects of enhanced continuous ambulatory peritoneal dialysis (CAPD) on the normalized protein catabolic rate (NPCR) and Kprt/V of two patients with zero residual renal function and marginal or below minimal HCFA values on urea kinetic modeling (Kprt/V = 0.21). Predictable increases in NPCR (from 0.61 to 0.76 and from 0.73 to 0.81 gm/kg/day, respectively) were seen after two weeks of enhanced CAPD achieved by the addition of a fifth nighttime exchange by a portable, easily operable, automated device (PD-PLUS).