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HLA class II nucleotide sequences, 1992.

S G Marsh1, J G Bodmer

  • 1Tissue Antigen Laboratory, Imperial Cancer Research Fund, London, United Kingdom.

Tissue Antigens
|November 1, 1992
PubMed
Summary
This summary is machine-generated.

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This compilation presents Human Leukocyte Antigen (HLA) Class II sequences, ensuring accuracy through author contact and incorporating amendments. It standardizes sequence data for research, using hyphens for identity and asterisks for unavailable sequences.

Area of Science:

  • Immunogenetics
  • Molecular Biology

Context:

  • Compiles Human Leukocyte Antigen (HLA) Class II sequences from established nomenclature publications.
  • Addresses discrepancies in reported sequences by contacting original authors for amendments.

Purpose:

  • To create an accurate and unified compilation of HLA Class II sequences.
  • To provide a reliable resource for researchers studying HLA genetics and immunology.

Summary:

  • Sequence alignments use hyphens (-) to indicate residue identity and asterisks (*) for unavailable sequences.
  • Gaps are strategically inserted to align diverse alleles with variations in amino acid numbering.
  • Emphasizes ongoing efforts to maintain data accuracy through community feedback.

Impact:

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  • Facilitates standardized research in HLA typing and transplantation.
  • Supports studies on immune system function and disease association.
  • Enhances the reliability of HLA sequence databases for global scientific use.