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Isolation of a new human pseudogene for proliferating cell nuclear antigen
Y Taniguchi1, Y Katsumata, S Koido
1Division of Molecular Life Science (Cell Biology), Tokai University School of Medicine, Kanagawa, Japan.
Nucleic Acids Symposium Series
|January 1, 1992
Abstract:
A new gene, which cross-hybridized with a rat PCNA cDNA probe, has been isolated from a human genomic cosmid library. A comparison of the gene with the human PCNA cDNA revealed 71% homology for the nucleotide sequences. This gene completely lacks introns and has traces of a polyA tail which the messenger RNA of the active gene retains. These facts indicate that this gene was generated by the reverse-transcription of a processed RNA for PCNA and exists as a PCNA pseudogene in the human genome.