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Updated: Aug 15, 2026

Expression of Recombinant Proteins in the Methylotrophic Yeast Pichia pastoris
Published on: February 26, 2010
Production of recombinant products in yeasts: a review
1Department of Biotechnology, Massey University, Palmerston North, New Zealand.
Abstract:
This paper reviews the use of yeasts to produce heterologous proteins via the development of transformation systems. The ability to genetically engineer yeast cells has many advantages over prokaryotic systems. Yeasts are already well established in fermentation procedures, are able to secrete glycosylated and modified proteins to render the proteins biologically active, and yeasts do not secrete toxic chemicals. With the techniques available it is possible to explore yeasts as hosts for the expression and secretion of commercially-useful proteins.
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