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Bacterial Artificial Chromosomes: A Functional Genomics Tool for the Study of Positive-strand RNA Viruses
Published on: December 29, 2015
Short report: a major genotype of Japanese encephalitis virus currently circulating in Japan
Shao-Ping Ma1, Yasuko Yoshida, Yoshihiro Makino
1Division of Epidemiology, Department of Infectious Diseases, Oita Medical University, Oita, Japan. masp@oita-med.ac.jp
Abstract:
A 240-nucleotide sequence of the capsid/premembrane gene region of 23 Japanese encephalitis virus (JEV) strains isolated in Tokyo and Oita, Japan was determined and phylogenetic analyses were performed. All the strains clustered into two distinct genotypes (III and I). All strains isolated before 1991 belonged to genotype III, while those isolated after 1994 belonged to genotype I. In addition, the strains of the genotype I isolated in Japan showed a close genetic relationship with those from Korea and Malaysia.
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