Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Recent Insights into HIV Accessory Proteins.

Jenny L. Anderson1, Thomas J. Hope

  • 1Department of Microbiology and Immunology, The University of Illinois at Chicago, Chicago, IL 60612, USA. thope@uic.edu

Current Infectious Disease Reports
|September 19, 2003
PubMed
Summary

Human immunodeficiency virus (HIV) accessory proteins are crucial for disease progression. This review focuses on recent discoveries concerning these proteins, particularly the viral infectivity factor (Vif), and potential therapeutic targets.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same journal

Chagas Disease: An Opportunistic Infection in AIDS.

Current infectious disease reports·2026
Same journal

Area-based Deprivation Indices and Healthcare-Associated Infections: A Narrative Review of Evidence.

Current infectious disease reports·2025
Same journal

Next Steps: Studying Diabetic Foot Infections with Next-Generation Molecular Assays.

Current infectious disease reports·2024
Same journal

To Tweet or Not to Tweet-a Review of the Viral Power of Twitter for Infectious Diseases.

Current infectious disease reports·2024
Same journal

Web alert.

Current infectious disease reports·2024
Same journal

Bacterial Vaginosis in Postmenopausal Women.

Current infectious disease reports·2023

Area of Science:

  • Virology
  • Molecular Biology
  • Immunology

Background:

  • Human immunodeficiency virus (HIV) utilizes structural, regulatory, and accessory proteins for replication.
  • Accessory proteins, including Nef, Vif, Vpr, and Vpu/Vpx, are vital for in vivo viral pathogenesis despite being dispensable for in vitro replication.
  • Understanding these proteins is critical for developing strategies against HIV.

Purpose of the Study:

  • To review recent advancements in the understanding of HIV accessory proteins.
  • To highlight key insights into the function of the viral infectivity factor (Vif).
  • To identify potential new therapeutic targets for HIV intervention.

Main Methods:

  • Literature review of recent research on HIV accessory proteins.

Related Experiment Videos

  • Analysis of studies focusing on the molecular mechanisms of Vif.
  • Synthesis of findings related to therapeutic strategies targeting HIV accessory proteins.

    • Main Results:

    • Recent studies have elucidated the complex roles of HIV accessory proteins in viral pathogenesis.
    • Breakthroughs in understanding the viral infectivity factor (Vif) protein's function have been achieved.
    • Several potential therapeutic targets within the accessory protein family have been identified.

    Conclusions:

    • HIV accessory proteins play essential roles in viral pathogenesis in vivo.
    • Further research into Vif and other accessory proteins offers promising avenues for novel antiviral therapies.
    • Targeting these proteins could lead to effective interventions against HIV.