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Anti-inflammatory effect of Solanum lycocarpum fruits
G Vieira1, P M Ferreira, L G Matos
1Instituto de Ciências Biológicas, Departamento de Ciências Fisiológicas, Universidade Federal de Goiás, Goiânia, Brazil.
Phytotherapy Research : PTR
|September 19, 2003
Abstract:
The croton oil-induced mouse ear oedema test, acetic acid-induced abdominal writhing, and carrageenan-induced peritonitis were used to study the anti-inflammatory effects of the crude ethanol extract and its alkaloid fraction from Solanum lycocarpum fruits. The alkaloid fraction induced a dose-dependent reduction in ear oedema formation and leukocyte migration, suggesting that S. lycocarpum fruits may contain steroidal alkaloids accounting for the anti-inflammatory effect of the crude ethanol extract.