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Published on: April 2, 2012
Carrier sequence selection--one key to successful vaccines
1Pharmaceutical Research New Technologies, F. Hoffmann-La Roche and Co. Ltd., Basel, Switzerland.
Immunology Today
|February 1, 1992
Abstract:
The trend towards epitopic vaccines has brought with it the problem of ensuring carrier function, a role previously filled by carrier sequences of the attenuated organism. Here, Howard Etlinger proposes the use of carrier epitopes, derived from vaccines already in use and selected for their ability to activate only helper T-cell responses, in the administration of B-cell-specific epitopic vaccines.

