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Roll, roll, roll your leucocyte gently down the vein
1Imperial Cancer Research Fund, London, UK.
The rapid advances being made in unravelling the biochemistry and function of the three categories of adhesion molecule involved in leucocyte-endothelial-cell interactions, namely selectins, integrins and the Ig super-family molecules, were highlighted at a recent meeting. In this short report, Nancy Hogg describes these developments and the prospects for anti-adhesion molecule therapy in the clinic.
The rapid advances being made in unravelling the biochemistry and function of the three categories of adhesion molecule involved in leucocyte-endothelial-cell interactions, namely selectins, integrins and the Ig super-family molecules, were highlighted at a recent meeting. In this short report, Nancy Hogg describes these developments and the prospects for anti-adhesion molecule therapy in the clinic.