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Differentiation therapy
1Division of Health Sciences, University of California, School of Medicine, Los Angeles.
Hematology/Oncology Clinics of North America
|June 1, 1992
Abstract:
A variety of compounds are able to induce myeloid leukemia cells to differentiate into morphologically and functionally mature cells. Vitamin D derivatives, retinoids, interferons, and polar-planar compounds are agents that demonstrate such activity in vitro and have been employed as therapy for the myelodysplastic syndromes.