[Cytostatic therapy in oto-rhino-laryngology (author's transl)]

The report covers the therapeutic results achieved after using cytostatic drugs in 104 patients treated at the 1st Oto-Rhino-Laryngological Univ. Hospital, Vienna, between 1967 and 1975. The breakdown according to the tumor histology shows that squamous cell carcinomas accounted for the highest per centage, i.e. 53%; laryngeal tumor prevails according to the tumor localization. In 42 patients it was not possible to positively influence the disease; 45 patients showed a disruption or a slowdown of the progress of the disease; in 17 patients all measurable criteria of the disease receded (classification according to Karnofsky). Even if the average survival time after the commencement of the therapy amounted to only about 6 months, it was nevertheless possible to positively influence the progress of the disease by means of cytosatic therapy.