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Olfactory bulb transplantation into the olfactory bulb of neonatal rats: a WGA-HRP study
T Zigova1, P P Graziadei, A G Monti-Graziadei
1Department of Biological Sciences, Florida State University, Tallahassee 32306.
Brain Research
|August 14, 1992
Abstract:
After unilateral bulbectomy in neonatal (P1-P5) rats, autoradiographically prelabeled presumptive olfactory bulbs from E15 and E17 embryos were transplanted in place of the removed tissue. After 2-7 months, the animals received injections of wheat germ agglutinin-horseradish peroxidase (WGA-HRP) into the piriform cortex. Nine of the twenty animals revealed WGA-HRP-positive neurons among neurons autoradiographically labeled, providing thus evidence that the axons of the output neurons from the homotopically transplanted olfactory bulb reconnect with the host piriform cortex.