Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Amyloid in prostatic corpora amylacea.

P A Cross¹, C J Bartley, J McClure

¹Department of Pathological Sciences, University of Manchester Medical School.

Journal of Clinical Pathology

|October 1, 1992

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Image reconstruction and analysis of atherosclerosis imaging by [<sup>18</sup>F]FDG PETCT using digital PET technology.

European journal of nuclear medicine and molecular imaging·2025

Same author

Observational study on antimicrobial resistance in <i>Escherichia coli</i> and <i>Salmonella</i> isolates from Ontario calf samples submitted to a diagnostic laboratory from 2007 to 2020.

The Canadian veterinary journal = La revue veterinaire canadienne·2022

Same author

Dairy producer satisfaction and knowledge transfer with the veterinary-administered risk assessment and management plan in a voluntary Johne's disease control program.

Journal of dairy science·2022

Same author

Associations between colostrum management, passive immunity, calf-related hygiene practices, and rates of mortality in preweaning dairy calves.

Journal of dairy science·2019

Same author

Demographic Factors Associated with Prince Edward Island Horse Farm Owner Awareness of the <i>Code of Practice for the Care and Handling of Equines</i>.

Journal of applied animal welfare science : JAAWS·2019

Same author

An observational study on passive immunity in Irish suckler beef and dairy calves: Tests for failure of passive transfer of immunity and associations with health and performance.

Preventive veterinary medicine·2018

Same journal

Defining biochemical, pathological and molecular factors prognostic in terms of disease control and survival in high-grade extremity soft tissue sarcoma: a scoping review.

Journal of clinical pathology·2026

Same journal

MILGDF: a multi-task, instance-level supervised model for oral squamous cell carcinoma integrating local-global attention and dynamic decision fusion.

Journal of clinical pathology·2026

Same journal

Paediatric B-lymphoblastic leukaemia with low peripheral blasts: a potential diagnostic pitfall.

Journal of clinical pathology·2026

Same journal

MRI-targeted versus systematic needle core biopsies in prostate cancer: a patient-based analysis of potential diagnostic and biologic underestimation.

Journal of clinical pathology·2026

Same journal

Basal plasmacytosis and eosinophilia for distinguishing inflammatory bowel disease from gastrointestinal tuberculosis on mucosal biopsy.

Journal of clinical pathology·2026

Same journal

Assay-dependent variability in free thyroxine (FT4): differential interference related to immunoassay design in a patient with subclinical hypothyroidism.

Journal of clinical pathology·2026

See all related articles

Amyloid is present in prostatic corpora amylacea, specifically composed of beta 2 microglobulin. This finding indicates a localized amyloidosis unrelated to kidney issues.

Area of Science:

Uropathology
Biochemistry
Immunohistochemistry

Background:

Prostatic corpora amylacea are common microscopic structures in the prostate.
The composition of these structures, particularly regarding amyloid deposition, has been a subject of investigation.

Purpose of the Study:

To investigate the presence and specific nature of amyloid within prostatic corpora amylacea.
To characterize the protein components of amyloid deposits in this prostatic tissue.

Main Methods:

Immunohistochemical staining of prostatic tissue specimens obtained from transurethral and open resections.
Utilized Congo red staining and antibodies against various proteins, including beta 2 microglobulin and prostatic specific antigen.

Main Results:

Related Experiment Videos

Amyloid was universally detected in all prostatic corpora amylacea examined.
Beta 2 microglobulin was consistently identified as a component of the amyloid deposits.

Conclusions:

Prostatic corpora amylacea represent a localized form of amyloidosis.
The amyloid in prostatic corpora amylacea originates from beta 2 microglobulin and is independent of chronic renal failure or dialysis.