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Isolated ventricular inversion with double inlet left ventricle.

R M Freedom, M Nanton, M R Dische

    European Journal of Cardiology
    |January 1, 1977
    PubMed
    Summary
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    Isolated ventricular inversion (IVI) is a rare heart defect where the ventricles are switched. Associated anomalies often complicate diagnosis and treatment, requiring differentiation from other complex congenital heart diseases.

    Area of Science:

    • Pediatric Cardiology
    • Congenital Heart Disease
    • Cardiac Morphology

    Background:

    • Isolated ventricular inversion (IVI) is a rare congenital cardiac anomaly.
    • It is characterized by ventricular inversion with subpulmonary conus and ventriculo-arterial concordance.
    • Understanding its diverse presentations is crucial for accurate diagnosis.

    Purpose of the Study:

    • To present two cases of IVI with double inlet right-sided morphologic left ventricle.
    • To review and analyze the angiocardiographic and pathologic features of 11 known IVI cases.
    • To highlight associated anomalies and their clinical implications.

    Main Methods:

    • Case presentation of two patients with IVI.
    • Review of existing literature on IVI.

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  • Analysis of angiocardiographic and pathological data from reported cases.

    • Main Results:

    • Eleven cases of IVI were analyzed, predominantly with levocardia and situs solitus.
    • Significant associated anomalies were frequent, including atrial and ventricular septal defects, and tricuspid valve abnormalities.
    • Two cases presented as IVI with double inlet left ventricle due to severe tricuspid valve obstruction.

    Conclusions:

    • IVI can mimic classical transposition physiology but is often complicated by numerous associated anomalies.
    • Accurate differentiation from other complex cardiac malpositions is essential.
    • This anomaly requires careful evaluation due to its high association with other cardiac defects.