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[Distribution of capsular serotypes in Klebsieela strains of enteral origin]
Abstract:
The significant proportion of microorganisms belonging to the Klebsiella genus among the causative agents isolated and subdifferentiation of the genus for epidemiological survey of infantile Klebsiella infections are dealt with in the present paper. The 28 Klebsiella strains isolated from cases of enteritis confirms the enteral tropism of these enterobacteria, especially among the infantile population. A proportion of 13.3% strains were identified in pure cultures obtained from feces and were considered as certainly enteropathogenic. The biochemical behaviour of the strains studied pointed to the ubiquity of the aerogenes biotype (76.9%) followed by the pneumoniae biotype (12.4%) and indol-positive Klebsiella strains (10.7%). Of the total 308 Klebsiella strains typed serologically with 80 OK capsular sera, 284 (92.2%) were listed in 63 serotypes, 13 of which (K7, K35, K47, K9, 530, K16, K1, K11, K18, K20, K37, K80, K i.e. 47.5%) were frequently identified in acute infantile cases of enterocolitis syndrome. Most of these serotypes are also considered endemo-epidemic by authors. Worthy of note among the Klebsiella types isolated in pure cultures from cases of infantile enteritis, was the prevalence of the aerogenes biotype, with a higher incidence of K1, K2, K16, K26, K44 serotypes, and of the indol-positive strains, with serotypes K13, K16, K65, K80.
Insights
Klebsiella bacteria are a significant cause of infantile enteritis. Specific serotypes and biotypes, particularly the aerogenes biotype, are frequently identified in these infections, highlighting their enteropathogenic potential.
Area of Science:
- Microbiology
- Infectious Diseases
- Epidemiology
Background:
- Klebsiella species are recognized as significant opportunistic pathogens.
- Infantile enteritis is a common gastrointestinal illness in infants.
- Understanding the epidemiology of Klebsiella infections in infants is crucial for public health.
Purpose of the Study:
- To investigate the prevalence and characteristics of Klebsiella strains causing infantile enteritis.
- To identify specific Klebsiella biotypes and serotypes associated with enteropathogenicity in infants.
- To contribute to the epidemiological survey of Klebsiella infections in the pediatric population.
Main Methods:
- Isolation and subtyping of Klebsiella strains from infantile enteritis cases.
- Biochemical characterization of isolated Klebsiella strains to determine biotypes.
- Serological typing of Klebsiella strains using 80 OK capsular sera.
- Analysis of the association between biotypes, serotypes, and enteropathogenicity.
Main Results:
- Klebsiella strains confirmed enteral tropism, with 13.3% identified as enteropathogenic from fecal samples.
- The aerogenes biotype (76.9%) was most prevalent, followed by pneumoniae (12.4%) and indol-positive strains (10.7%).
- Of 308 strains typed, 92.2% belonged to 63 serotypes; 13 specific serotypes accounted for 47.5% and were frequently found in acute infantile enterocolitis.
Conclusions:
- Certain Klebsiella serotypes and the aerogenes biotype are frequently implicated in infantile enteritis.
- Specific serotypes (e.g., K1, K2, K16, K26, K44) within the aerogenes biotype and indol-positive strains (e.g., K13, K16, K65, K80) are noteworthy.
- Findings support the endemo-epidemic nature of specific Klebsiella serotypes in infantile enterocolitis.