Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Perceptual Constancy01:12

Perceptual Constancy

1.8K
Perceptual constancy is the ability to recognize that objects remain consistent and unchanged even when their appearance varies due to changes in sensory input. There are four main types of perceptual constancy: size constancy, shape constancy, color constancy, and brightness constancy.
Size constancy is the recognition that an object remains the same size, even when its image on the retina changes. For instance, a bus is perceived to be large enough to carry people, even if it looks tiny from...
1.8K
Depth Perception and Spatial Vision01:15

Depth Perception and Spatial Vision

2.6K
Depth perception is the ability to perceive objects three-dimensionally. It relies on two types of cues: binocular and monocular. Binocular cues depend on the combination of images from both eyes and how the eyes work together. Since the eyes are in slightly different positions, each eye captures a slightly different image. This disparity between images, known as binocular disparity, helps the brain interpret depth. When the brain compares these images, it determines the distance to an object.
2.6K
Difference from Background: Limit of Detection01:05

Difference from Background: Limit of Detection

9.1K
The limit of detection (LOD) is the smallest amount of analyte that can be distinguished from the background noise. The LOD value corresponds to the concentration at which the analyte signal is three times larger than the standard deviation of the blank signal. Below this value, the analyte signal cannot be differentiated from the background noise. It is calculated by dividing the calibration slope by 3 times the standard deviation of the blank signals.
The LOD indicates the presence or absence...
9.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Proton beam radiotherapy for choroidal and ciliary body melanoma in the UK-national audit of referral patterns of 1084 cases.

Eye (London, England)·2022
Same author

Photodynamic therapy as initial treatment for small choroidal melanomas.

Photodiagnosis and photodynamic therapy·2017
Same author

Conjunctival squamous cell neoplasia: the Liverpool Ocular Oncology Centre experience.

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie·2014
Same author

Lack of BAP1 protein expression in uveal melanoma is associated with increased metastatic risk and has utility in routine prognostic testing.

British journal of cancer·2014
Same author

Molecular pathology of uveal melanoma.

Eye (London, England)·2012
Same author

Conjunctival melanoma and melanocytic intra-epithelial neoplasia.

Eye (London, England)·2012
Same journal

Automated deep learning-based retinoschisis and detachment volume measurement in pathological myopia with posterior scleral contraction.

The British journal of ophthalmology·2026
Same journal

Bacterial keratitis: a global review of current practices, challenges and innovations.

The British journal of ophthalmology·2026
Same journal

Real-world integration of an autonomous artificial intelligence system for diabetic retinopathy screening in an endocrinology outpatient clinic.

The British journal of ophthalmology·2026
Same journal

Maternal smoking during pregnancy: a risk factor for early childhood ophthalmologic conditions.

The British journal of ophthalmology·2026
Same journal

Clinical characteristics and <i>ompA</i> serovar correlation in adult inclusion conjunctivitis: a cohort study in China.

The British journal of ophthalmology·2026
Same journal

Drusen volume and reticular pseudodrusen volume from optical coherence tomography with deep learning as risk factors for progression to late age-related macular degeneration in eyes with reticular pseudodrusen and contralateral macular neovascularisation.

The British journal of ophthalmology·2026
See all related articles

Related Experiment Video

Updated: Mar 31, 2026

Using Looming Visual Stimuli to Evaluate Mouse Vision
05:07

Using Looming Visual Stimuli to Evaluate Mouse Vision

Published on: June 13, 2019

12.5K

The dark perimetric stimulus.

E Mutlukan1, B E Damato

  • 1Tennent Institute of Ophthalmology, University of Glasgow.

The British Journal of Ophthalmology
|May 1, 1992
PubMed
Summary
This summary is machine-generated.

Dark stimuli are less visible than bright stimuli, with ambient light affecting bright stimuli more. This study explored visual field eccentricities under varying illumination conditions.

More Related Videos

An Operant Intra-/Extra-dimensional Set-shift Task for Mice
08:35

An Operant Intra-/Extra-dimensional Set-shift Task for Mice

Published on: January 22, 2016

12.9K
Human Fear Conditioning Conducted in Full Immersion 3-Dimensional Virtual Reality
10:38

Human Fear Conditioning Conducted in Full Immersion 3-Dimensional Virtual Reality

Published on: August 10, 2010

21.6K

Related Experiment Videos

Last Updated: Mar 31, 2026

Using Looming Visual Stimuli to Evaluate Mouse Vision
05:07

Using Looming Visual Stimuli to Evaluate Mouse Vision

Published on: June 13, 2019

12.5K
An Operant Intra-/Extra-dimensional Set-shift Task for Mice
08:35

An Operant Intra-/Extra-dimensional Set-shift Task for Mice

Published on: January 22, 2016

12.9K
Human Fear Conditioning Conducted in Full Immersion 3-Dimensional Virtual Reality
10:38

Human Fear Conditioning Conducted in Full Immersion 3-Dimensional Virtual Reality

Published on: August 10, 2010

21.6K

Area of Science:

  • Ophthalmology
  • Visual Neuroscience
  • Perception

Background:

  • Understanding visual perception is crucial for diagnosing and treating visual field defects.
  • The visibility of stimuli is influenced by background luminance and surrounding illumination.
  • Disappearance eccentricity, a measure of visual field sensitivity, is not fully characterized for different stimulus types.

Purpose of the Study:

  • To determine the disappearance eccentricities of dark and bright stimuli in the central visual field.
  • To investigate the impact of varying surrounding illumination levels on stimulus visibility.
  • To compare the visibility of dark versus bright stimuli under different luminance conditions.

Main Methods:

  • Utilized oculokinetic perimetry technique.
  • Measured disappearance eccentricities of equally sized dark and bright stimuli.
  • Assessed stimuli in the inferonasal central visual field.
  • Varied levels of surrounding illumination and background luminance.

Main Results:

  • Dark stimuli on bright backgrounds exhibited smaller 'isoptres' (visibility zones) than bright stimuli on dark backgrounds.
  • Variations in ambient illumination and background luminance had a lesser effect on the visibility of dark stimuli compared to bright stimuli.
  • The study quantified differences in visual field sensitivity based on stimulus polarity and background luminance.

Conclusions:

  • The visibility and characteristics of visual field 'isoptres' differ significantly between dark and bright stimuli.
  • Ambient illumination plays a more critical role in modulating the visibility of bright stimuli than dark stimuli.
  • Findings contribute to a better understanding of visual field testing and the factors influencing stimulus detection.