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Red eyes in renal failure.

N Klaassen-Broekema1, O P van Bijsterveld

  • 1Department of Ophthalmology, Utrecht State University, The Netherlands.

The British Journal of Ophthalmology
|May 1, 1992
PubMed
Summary

Patients with chronic renal failure and eye calcification experienced red eye symptoms. Elevated serum calcium levels correlated with inflammatory eye conditions, suggesting a specific "red eye of renal failure".

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Area of Science:

  • Ophthalmology
  • Nephrology
  • Pathology

Background:

  • Patients with chronic renal failure often exhibit calcium salt deposition in ocular tissues.
  • Ocular surface calcification can lead to various clinical presentations.

Purpose of the Study:

  • To investigate the spectrum of inflammatory eye conditions associated with ocular calcification in chronic renal failure patients.
  • To determine the correlation between serum calcium levels and the severity of ocular inflammation.

Main Methods:

  • Retrospective analysis of 57 chronic renal failure patients with conjunctival and corneal calcification.
  • Clinical examination and assessment of serum calcium concentrations.
  • Categorization of patients based on ocular inflammatory signs.

Main Results:

  • Two patients experienced acute conjunctivitis with corneal epithelial erosions due to calcium concretion exfoliation.
  • Eight patients presented with conjunctival inflammation resembling pingueculitis.
  • Three patients exhibited diffuse episcleral and conjunctival hyperemia, associated with significantly higher serum calcium levels.
  • Serum calcium levels were significantly higher in patients with inflammatory signs compared to those without or with pingueculitis.

Conclusions:

  • Ocular calcification in chronic renal failure can manifest as distinct inflammatory syndromes.
  • Elevated serum calcium is a key factor in the development of severe ocular inflammation.
  • Proposes the term 'red eye of renal failure' for specific inflammatory presentations.

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