Combination of treatment with perfluorochemicals and free radical scavengers

¹Physiologisches Institut, Univ. Wuerzburg, FRG.

Biomaterials, Artificial Cells, and Immobilization Biotechnology : Official Journal of the International Society for Artificial Cells and Immobilization Biotechnology

|January 1, 1992

Abstract:

P-cyclohexylmorpholine, given as oxygen carrier of second generation, was tested in two experimental models: the ischemic intestine and the lung under hyperbaric oxygen condition. In both instances in separated groups either alpha-tocopherol or allopurinol was additionally given as oxygen free radical scavenger. The thiobarbituric acid reaction (TBAR) was used as screening test for the occurrence of lipid peroxidation in organ probes; further the content of glutathione in reduced (GSH) and oxidized form (GSSG) was determined. Whereas only slight increases of TBAR substances and GSSG could be found compared to controls, the effect of the administrated scavenging drugs was very impressive: they could suppress nearly totally the effect of an enhanced oxidative stress.

Related Experiment Videos

Combination of treatment with perfluorochemicals and free radical scavengers

Related Concept Videos

[Structural and process parameters of interdisciplinary multimodal pain therapy in Germany-an update].

[The judgment of the Federal Social Court on the involvement of psychological psychotherapists in interdisciplinary multimodal pain therapy : A critical comment].

[Is interdisciplinary multimodal pain therapy threatened? : Increasing controversy on the necessity for inpatient treatment].

[Traveling with immunodeficiency-Problems and prevention].

[Cross-sectoral interdisciplinary multimodal pain therapy : Recommendations on structural and process parameters of the ad hoc commission "Interdisciplinary Multimodal Pain Therapy" of the German Pain Society (Deutsche Schmerzgesellschaft e. V.)].

Training emotion regulation through real-time fMRI neurofeedback of amygdala activity.

Skin sensitization study of a new BIS-GMA based dental restorative material.

The long-term observation of the transplantation of encapsulated rat islets to the diabetic mice.

Preparation and evaluation in vitro and vivo of copoly (lactic/glycolic) acid microspheres containing norethisterone.

In vitro toxicity of biomaterials determined with cell density, total protein, cell cycle distribution and adenine nucleotides.

Preservation of regional and global left ventricular function by intracoronary infusion with oxygenated fluorocarbon emulsion Therox in dogs.

Release of chemicals from polyurethane foam in the Même breast implant.

Persistent open-shell acridinyl radical enables long-wavelength photoreduction.

Multifunctional O‑Acyloximes as Near-UV- and Visible Light-Sensitive Photoinitiators.

Chitosan-Coated Quercetin Nanoemulsion Eye Drops for Sustained Ocular Delivery and Protection of Lens Degeneration from Oxidative Stress.

Open Posterolateral Elbow Dislocation in an Adult after Low-Energy Trauma: A Case Report Highlighting Diagnostic and Operative Considerations.

A Low-Oxidation-State Mechanism for O─O Bond Formation in Photosystem II via Oxo-Hydroxyl Radical Coupling.

Highly oxidized products from the atmospheric reaction of hydroxyl radicals with toluene.

Related Experiment Videos

Combination of treatment with perfluorochemicals and free radical scavengers

Abstract:

Related Concept Videos

Related Articles