Related Experiment Video
Updated: Aug 9, 2026

The 5-Choice Serial Reaction Time Task: A Task of Attention and Impulse Control for Rodents
Published on: August 10, 2014
Behavioral effects of caffeine, methamphetamine, and methylphenidate in the rat
Abstract:
It was possible to distinguish three closely-related psychomotor stimulants, caffeine, methamphetamine, and methylphenidate, by means of two operant behavior procedures, fixed interval and fixed number. Under the fixed interval procedure, the percentage change in the number of R(B)s per reinforcement was significantly smaller with caffeine than with methamphetamine or methylphenidate (p < .001). Under the fixed number procedure, the percentage change was significantly smaller with methamphetamine than with caffeine or methylphenidate (p < .001). Thus, methylphenidate had a methamphetamine-like effect under fixed interval and a caffeine-like effect under fixed number.
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