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The uptake of anionic and cationic amino acids by the isolated perfused sheep choroid plexus
1Sherrington School of Physiology, United Medical School, Guy's Hospital, London, UK.
Brain Research
|May 29, 1992
Abstract:
The carrier-mediated uptake of anionic and cationic amino acids by the basolateral face (blood side) of the isolated perfused sheep choroid plexus was demonstrated using the paired-tracer dilution technique. The uptake of these two classes of amino acid was higher than at the blood-brain barrier with no cross-competition between them. In addition the uptake was markedly stereospecific with a high degree of selectivity and no interaction with the L-system amino acids.