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Isolation and structures of antibacterial binaphtho-alpha-pyrones, talaroderxines A and B, from Talaromyces derxii
K Suzuki1, K Nozawa, S Nakajima
1Faculty of Pharmaceutical Sciences, Hoshi University, Tokyo, Japan.
Chemical & Pharmaceutical Bulletin
|May 1, 1992
Abstract:
New compounds designated talaroderxines A (1) and B (2) were isolated from a new heterothallic ascomycetous fungus, Talaromyces derxii, cultivated on rice. The structures of 1a and 1b were elucidated by means of spectroscopic examination and chemical reactions. Talaroderxines A (1a) and B (1b) are atropisomers of a 6,6'-binaphtho-alpha-pyrone derivative, and have strong antibacterial activity against Bacillus subtilis.