Foveal flicker sensitivity discriminates ARM-risk from healthy eyes

The "good" eyes of 13 patients with monocular exudative ARM were compared with age-matched healthy eyes of 19 subjects. Membership in the two study groups was based upon careful clinical evaluation of the tested eye as well as upon status of the fellow eye. We asked whether temporal contrast sensitivity for a long-wavelength, low spatial frequency stimulus can be used to identify the group in which a given eye belongs. Using step-wise discriminant analysis, we found that the ARM-risk and healthy eyes could be classified with 78% accuracy on the basis of foveal flicker sensitivity at two temporal frequencies--14 and 10 Hz (in order of estimated weight.)