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Related Experiment Videos

Relationship between body and leg VO2 during maximal cycle ergometry.

D R Knight¹, D C Poole, W Schaffartzik

¹Department of Medicine, University of California, San Diego, La Jolla 92093-0623.

Journal of Applied Physiology (Bethesda, Md. : 1985)

|September 1, 1992

Summary

The maximal oxygen uptake (VO2) in the whole body plateaus at maximal work rates, mirroring the oxygen consumption in exercising legs. This finding confirms that leg oxygen uptake explains whole-body VO2 behavior during intense exercise.

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Area of Science:

Exercise Physiology
Human Physiology
Sports Science

Background:

The relationship between whole-body oxygen consumption (VO2) and maximal work rates (WR) is not fully understood.
It remains unclear if the asymptotic behavior of VO2 at maximal WRs is driven by the VO2 dynamics in the exercising muscles.

Purpose of the Study:

To investigate whether the oxygen consumption (VO2) in the exercising legs explains the asymptotic behavior of whole-body VO2 at maximal work rates (WR).

Main Methods:

Simultaneous measurements of whole-body and leg VO2 were conducted in trained male cyclists during incremental cycle ergometry under normoxic and hypoxic conditions.
Leg blood flow was measured using constant-infusion thermodilution.
Leg VO2 was calculated from leg blood flow and arterial-femoral venous oxygen content difference.

Keywords:

NASA Discipline Cardiopulmonary Non-NASA Center

Related Experiment Videos

Main Results:

Both whole-body and leg VO2 demonstrated reproducible asymptotic behavior at maximal work rates.
The plateauing of leg VO2 was attributed to concurrent limitations in leg blood flow and oxygen extraction.
There was no significant difference between the extrapolated and measured maximal VO2 for either the whole body or the legs.

Conclusions:

The asymptotic behavior of whole-body oxygen consumption (VO2) at maximal work rates is a direct reflection of the VO2 profile within the exercising legs.
Leg oxygen uptake is the primary determinant of whole-body VO2 limitations during maximal exercise.