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Updated: Jul 20, 2026

Prehospital Thrombolysis: A Manual from Berlin
Published on: November 26, 2013
Approach to the patient with venous thromboembolism. Treatment with thrombolytic agents
A A Sasahara1, C C St Martin, J Henkin
1Pharmaceutical Products Division, Abbott Laboratories, Abbott Park, Illinois.
This article reviews the different thrombolytic agents currently available and the different mechanisms by which they activate the body's fibrinolytic system. The discussion is confined to the approach to the patient with venous thromboembolism using the different thrombolytic agents. Data are presented supporting the use of thrombolytic therapy and its long-term benefits, especially in patients with pulmonary embolism. A substantial portion of this article is devoted to practical considerations involved in the administration of thrombolytic therapy.
This article reviews the different thrombolytic agents currently available and the different mechanisms by which they activate the body's fibrinolytic system. The discussion is confined to the approach to the patient with venous thromboembolism using the different thrombolytic agents. Data are presented supporting the use of thrombolytic therapy and its long-term benefits, especially in patients with pulmonary embolism. A substantial portion of this article is devoted to practical considerations involved in the administration of thrombolytic therapy.
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Pulmonary Embolism III: Nursing Management

