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Updated: Aug 13, 2026

Static Adhesion Assay for the Study of Integrin Activation in T Lymphocytes
Published on: June 13, 2014
Role of adhesion molecules in cutaneous inflammation and neoplasia
1Department of Dentistry, University of Queensland, Brisbane, Australia.
Abstract:
There is accumulating evidence that the expression of certain adhesion molecules has important consequences for understanding patterns of cell movement in normal and pathologically altered skin. This paper reviews recent work regarding the role of integrins and other adhesion molecules (ICAM-1, VCAM-1, PECAM-1, LECAM-1, and ELAM-1) in cutaneous inflammation and neoplasia, and presents a unifying hypothesis which outlines how sequential expression of cytokines and adhesion molecules in evolving inflammation may alter the nature of the cellular response.
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