Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Different spatial tunings for ON and OFF pathway stimulation.

C W Tyler1, H Chan, L Liu

  • 1Smith-Kettlewell Eye Research Institute, San Francisco, CA 94115.

Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)
|April 1, 1992
PubMed
Summary

Visual system processing differs for light increments versus decrements. Spatial tuning reveals distinct sensitivity and masking behaviors, suggesting separate neural pathways for ON and OFF visual processing systems.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Vision and leadership in advancing healthcare: a conversation with Professor Justin Wu.

Hong Kong medical journal = Xianggang yi xue za zhi·2025
Same author

Complexity and weak integration promote the diversity of reef fish oral jaws.

Communications biology·2024
Same author

High-'n'-dry? A comparison of cannabis and alcohol use in drivers presenting to hospital after a vehicular collision.

Addiction (Abingdon, England)·2023
Same author

Scleritis and choroidal granuloma in a young patient with sarcoidosis.

Journal francais d'ophtalmologie·2022
Same author

Plant-Based Dietary Patterns, Body Composition, Muscle Strength and Function in Middle and Older Age: A Systematic Review.

The journal of nutrition, health & aging·2021
Same author

Idiopathic choroidal neovascularization in a young boy.

Journal francais d'ophtalmologie·2021

Area of Science:

  • Visual Neuroscience
  • Sensory Processing
  • Computational Vision

Background:

  • The visual system distinguishes between light increments (ON pathway) and decrements (OFF pathway).
  • Understanding the spatial tuning of these pathways is crucial for comprehending visual perception.

Purpose of the Study:

  • To compare the spatial tuning of sensitivity to luminance increments and decrements.
  • To investigate how luminance bias affects spatial tuning and contrast masking.

Main Methods:

  • Used spatiotemporal Gabor grating functions with positive (increment) or negative (decrement) luminance bias.
  • Employed a contrast self-masking paradigm with biased Gabor modulation.
  • Analyzed detection of spots with a 2-D difference-of-Gaussian profile.

Related Experiment Videos

Main Results:

  • Positive luminance bias (increments) showed narrower spatial tuning bandwidth and greater peak sensitivity compared to negative bias (decrements).
  • Asymmetry in masking functions observed at low spatial frequencies, with negative bias stimuli yielding a flat masking function.
  • Biased masking functions at medium spatial frequencies resembled typical unbiased gratings, showing facilitation and sub-Weber masking.

Conclusions:

  • Stimuli without abrupt luminance transients exhibit distinct spatial tuning for positive and negative stimuli.
  • These differences likely reflect variations in neural connectivity between the visual system's ON and OFF processing pathways.