[Insulin treatment--its physiological principle]

Insulin treatment based on the physiological principle not only results in better glucose homeostasis but also in improved quality of life for the patients. The frequency of metabolic events also seems to be controlled, particularly when the multiple injection system is used. However, a prerequisite is regular, preferably daily, blood sugar monitoring to enable the insulin dosage to be adapted according to food intake and exercise. Advances in our knowledge of the importance of the injection technique used may contribute to the optimisation of insulin treatment and thus of glucose homeostasis.