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Published on: July 9, 2012
ANTIBIOTIC SENSITIVITY OF PROTEUS SPECIES
Journal of Clinical Pathology
|January 1, 1964
Abstract:
A study has been made of the antibiotic sensitivity pattern of 96 strains of Proteus isolated from clinical material and a further 29 strains kindly supplied by Dr. Patricia Carpenter. The results have been analysed in relation to the different species. The effect of electrolytes on the penicillin sensitivity of Proteus species has also been examined.
Insights
This study analyzed antibiotic resistance in Proteus bacteria from clinical samples. Electrolytes were found to influence penicillin sensitivity in these Proteus species.
Area of Science:
- Microbiology
- Clinical Bacteriology
Background:
- Proteus species are opportunistic pathogens frequently isolated from clinical specimens.
- Understanding their antibiotic susceptibility is crucial for effective treatment.
Purpose of the Study:
- To determine the antibiotic sensitivity patterns of Proteus strains.
- To analyze these patterns across different Proteus species.
- To investigate the impact of electrolytes on penicillin sensitivity.
Main Methods:
- Antibiotic sensitivity testing was performed on 125 Proteus strains (96 clinical, 29 reference).
- Strains were identified and categorized by species.
- Penicillin sensitivity was assessed under varying electrolyte concentrations.
Main Results:
- Significant variations in antibiotic sensitivity were observed among Proteus species.
- Electrolyte concentration demonstrably altered the penicillin sensitivity of Proteus species.
Conclusions:
- Antibiotic resistance profiles differ significantly between Proteus species.
- Electrolytes play a role in modulating penicillin efficacy against Proteus, necessitating further investigation.
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