[Some Spanish contributions to anesthesiology at the end of the XIXth century]

At the end of the XIXth century some original, although poorly known, Spanish contributions were made on the field of inhalational general anesthesia that are important for the history of our specialty in Spain. The purpose of this work is to report the Spanish contributions to inhalational general anesthesia made during the chronological period that coincides with the locus-regional anesthetic techniques grown after the appearance of cocaine in 1884.