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[Malaria and pregnancy].

A L Hoffmann1, A M Rønn, J Langhoff-Roos

  • 1Rigshospitalet, København.

Ugeskrift for Laeger
|September 21, 1992
PubMed
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This summary is machine-generated.

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Malaria in pregnancy can cause severe complications, even years after exposure. Early diagnosis and specialized treatment are crucial for successful outcomes in pregnant women, emphasizing combined prevention strategies.

Area of Science:

  • Obstetrics and Gynecology
  • Infectious Diseases
  • Tropical Medicine

Background:

  • Malaria is a significant cause of adverse pregnancy outcomes in endemic areas.
  • While rare in Denmark, imported malaria cases in pregnant women require careful management.

Observation:

  • Four pregnant patients with malaria were treated at a Copenhagen hospital.
  • Two patients required emergency Cesarean sections due to intrauterine asphyxia.
  • Delayed presentation for treatment was noted, linked to unawareness of delayed malaria manifestation.

Findings:

  • All four pregnancies were successful despite the malaria diagnosis.
  • Three of the four patients had used malaria prophylaxis, indicating evolving resistance or inadequate protection.
  • Current malaria treatment guidelines for pregnant women include chloroquine, mefloquine (with caution), and quinine for severe cases.

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Implications:

  • Healthcare providers and patients need awareness regarding the potential for malaria to manifest years post-exposure.
  • Chemoprophylaxis should be augmented with mechanical protection and insect repellents due to increasing drug resistance.
  • Pregnant women with malaria require specialized monitoring in maternity units and collaboration with tropical medicine experts.