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[Allergic reactions to teniposide (VM-26) in children with neoplasms]
M Wysocki1, A Nowaczyk-Michalak, O Pilecki
1Katedra i I Klinika Chorób Dzieci Ak. Med., Bydgoszczy.
Wiadomosci Lekarskie (Warsaw, Poland : 1960)
|February 1, 1992
Abstract:
Allergic reactions of dramatic intensity were observed in 5 children treated with Teniposide (VM-26) for acute lymphoblastic leukaemia and histiocytosis X. In the further treatment this drug was replaced with epoxide, a cytostatic agent which is also a podophyllin derivative but in other chemical formulation. In none of these patients the allergic reaction returned.