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Sequence-specific and Selective Recognition of Double-stranded RNAs over Single-stranded RNAs by Chemically Modified Peptide Nucleic Acids
09:04

Sequence-specific and Selective Recognition of Double-stranded RNAs over Single-stranded RNAs by Chemically Modified Peptide Nucleic Acids

Published on: September 21, 2017

PURINE- AND PYRIMIDINE-SPECIFIC ANTIBODIES: EFFECT ON THE FERTILIZED SEA URCHIN EGG

H S ROSENKRANZ, B F ERLANGER, S W TANENBAUM

    Science (New York, N.Y.)
    |July 17, 1964
    PubMed

    Antiserums from rabbits immunized with several purine- and pyrimidine-containing albumin conjugates can penetrate and become fixed within cells of Arbacia punctulata. All of these specific antiserums were found to inhibit embryonic development of the fertilized sea urchin egg. The stage of arrestment of development was dependent in part upon the dilution of antiserum, and also upon the nature of its specificity. It is suggested that the observed results reflect the interaction of these antiserums with singlestranded DNA within the cell.

    Keywords:
    ANTIBODIESECHINODERMATAEXPERIMENTAL LAB STUDYIMMUNE SERUMSOVUMPURINESPYRIMIDINESRABBITS

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