Related Experiment Videos
Inferior vena cava filters. Indications, safety, effectiveness
D M Becker1, J T Philbrick, J B Selby
1Department of Internal Medicine, University of Virginia Health Sciences Center, Charlottesville 22908.
Archives of Internal Medicine
|October 1, 1992
Summary
Inferior vena cava (IVC) filters effectively prevent pulmonary embolism, but their indications, safety, and effectiveness require further study. Optimal use involves experienced clinicians and collaboration for patient care.
Area of Science:
- Vascular Surgery
- Interventional Radiology
- Cardiology
Background:
- Inferior vena cava (IVC) filters aim to prevent pulmonary embolization by interrupting blood flow.
- Despite widespread use, the clinical utility and safety of IVC filters remain incompletely evaluated.
- Numerous case series exist, but controlled trials are lacking.
Purpose of the Study:
- To systematically review published studies on IVC filters.
- To clarify indications, safety, and effectiveness based on existing literature.
Main Methods:
- MEDLINE database search for English-language publications since 1970 with follow-up data.
- Review of eight methodologic guidelines to assess scientific quality.
- Analysis of 24 case series (16 on Greenfield, 8 on newer designs).
Main Results:
- Recurrent pulmonary embolism was rare post-filter placement.
- Filter complications were common but rarely life-threatening; four deaths reported.
- Thrombotic complications, including DVT and IVC obstruction, occurred rarely with all filter types.
Conclusions:
- IVC filters appear effective in preventing recurrent pulmonary embolism.
- Further research is needed to fully understand indications, safety, and effectiveness.
- Anticoagulant therapy is recommended with filters; filter selection requires expertise and collaboration.