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Pyrrylphenylethanones related to cathinone and lefetamine: synthesis and pharmacological activities
1Dipartimento di Studi farmaceutici, Università di Roma, La Sapienza, Italy.
Archiv Der Pharmazie
|July 1, 1992
Abstract:
The synthesis of various pyrrylphenylethanones resembling cathinone and lefetamine is described starting from 2-chloro-1-(1-methyl-1H-pyrrol-2-yl)-2-phenylethan-1-one. Some derivatives showed good antinociceptic activity, comparable to that of morphine. The neuropsychopharmacological profile of title compounds has been also studied to explore their action on C.N.S.