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Published on: May 7, 2015
Coronary risk in spinal cord injury: assessment following a multivariate approach
D Cardús1, F Ribas-Cardús, W G McTaggart
1Baylor College of Medicine, Department of Physical Medicine and Rehabilitation, Houston, TX.
Insights
Men with spinal cord injury (SCI) do not face a higher risk of coronary heart disease compared to able-bodied individuals. SCI risk for coronary artery disease is similar to the general population and not linked to injury duration.
Area of Science:
- Cardiology
- Neurology
- Public Health
Background:
- Spinal cord injury (SCI) can impact cardiovascular health.
- Assessing coronary heart disease (CHD) risk in SCI patients is crucial for preventative care.
Purpose of the Study:
- To determine if individuals with spinal cord injury have an elevated risk of coronary heart disease.
- To compare CHD risk in SCI patients with age-matched, able-bodied controls.
Main Methods:
- A cohort of 96 men with SCI was studied.
- The Framingham study's multivariate approach was used to estimate 6-year CHD probability.
- Data were compared against 96 non-trained, able-bodied men matched for age.
Main Results:
- Patients with SCI exhibited a CHD risk similar to that of the control group.
- Risk increased with age but remained comparable to the general population.
- No significant correlation was found between CHD risk and the duration of SCI.
Conclusions:
- Spinal cord injury does not appear to independently increase coronary heart disease risk.
- Age is a significant factor in CHD risk for SCI patients, similar to the general population.
- The study could not conclude if lesion level is an independent risk factor.
Abstract:
A group of 96 men with spinal cord injury was studied to find out if patients with spinal cord injury were at an increased risk of coronary heart disease. A multivariate approach based on data produced by the Framingham study was used to estimate the probability of developing coronary artery disease within six years. Data obtained from the 96 patients were compared with data obtained from 96 nontrained, able-bodied men matched according to age. The results of this study suggest that patients with spinal cord injury show a risk of coronary artery disease similar to that estimated in non-trained, age-matched, able-bodied individuals. The risk increases with age, but it is of the same order as that found in the normal population and does not appear to be related to the duration of the disease. The results are inconclusive in regard to the level of the lesion as an independent factor of risk.
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