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Thrombolytic therapy for right heart lesions
A Yunus1, C A Basualdo, K Kavanagh
1Division of Cardiology, Walter C Mackenize Health Sciences Centre, Edmonton, Alberta.
The Canadian Journal of Cardiology
|October 1, 1992
Summary
Fibrinolytic therapy shows promise for treating right heart clots, offering a potential alternative to surgery. This approach may stabilize patients, providing crucial time for surgical preparation and reducing embolization risks.
Area of Science:
- Cardiology
- Vascular Medicine
- Thrombosis Research
Background:
- Thrombolytic agents are standard for arterial and venous thromboses.
- Limited data exist on thrombolysis for right heart clots, particularly in complex cardiac histories.
Observation:
- Two patients with prior cardiac surgeries received fibrinolytic therapy for right heart thrombosis.
- Case 1: Prosthetic pulmonary valve thrombosis. Case 2: Tricuspid atresia with Fontan duct stenosis and right atrial clot.
Findings:
- Fibrinolytic therapy was explored as a treatment for thrombosis in right heart structures.
- The therapy was considered a potential safe alternative to surgery in these cases.
Implications:
- Thrombolytic therapy may offer a less invasive option for right heart clot management.
- Even partial effectiveness can facilitate surgical preparation and mitigate risks during intervention.