Related Experiment Videos
PEO enhancement of platelet deposition, fibrinogen deposition, and complement C3 activation
E L Chaikof1, E W Merrill, A D Callow
1Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge 02139.
Journal of Biomedical Materials Research
|September 1, 1992
Abstract:
Whereas it has been commonly thought that adding polyethylene oxide PEO to a surface would diminish the capacity of the surface to cause deposition of platelets and of fibrinogen, and to activate complement C3, we present data showing exactly the opposite. These unexpected results are obtained with low molecular weight (2000) PEO, and are not found with higher molecular weight (20,000) PEO.