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Updated: Aug 2, 2026
10:25
Assessment of Lymphocyte Migration in an Ex Vivo Transmigration System
Published on: September 20, 2019
Cutaneous larva migrans, an occupational disease
Annals of Clinical and Laboratory Science
|September 1, 1977
Summary
Veterinarians and lab workers can contract creeping skin eruption from horse Strongyloides larvae. Repeated exposure can cause severe hyperimmune reactions due to parasitic protein hypersensitivity.
Area of Science:
- Veterinary parasitology
- Dermatology
- Infectious diseases
Background:
- Creeping skin eruption is typically linked to canine and feline hookworm larvae in tropical/subtropical areas.
- A less recognized risk involves veterinarians and lab workers exposed to equine Strongyloides larvae in temperate zones.
Observation:
- This study details the evolving clinical presentation of Strongyloides infection in humans.
- The research highlights the potential for severe hyperimmune reactions following repeated exposure.
Findings:
- Strongyloides larvae can penetrate intact skin, causing significant pathological changes.
- Demonstrated invasiveness and effects in a rabbit model.
Implications:
- Highlights a specific occupational hazard for those working with horses.
- Emphasizes the need for awareness and preventive measures against Strongyloides infection in veterinary and laboratory settings.
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