[Suppressor cells in the "in vitro" induced cell mediated immune response: their origin and target (author's transl)]

Suppressor cells, produced in a mixed lymphocyte reaction between CBA and irradiated DBA/2 lymphocytes, inhibited the production of cytotoxic CBA cells in a second MLR. There were several suppressor cells: T and non-T cells, cells with or without Fc-receptors, and cytotoxic as well as non-cytotoxic cells. Reconstitution of the in vitro production of cytotoxic as well as non-cytotoxic cells. Reconstitution of the in vitro production of cytotoxic lymphocytes in suppressed cultures by supplementary CBA cells was better than that which took place after the addition of DBA/2 stimulator cells.