[Influence of temperature on insulin secretion induced by different concentrations of glucose]

Lowering of the temperature from 37.5 degrees C to 28 degrees C provokes a decrease in the response of the beta cell to the stimulation by glucose (1.5 g/1, 3 g/1 and 5 g/1). The insulin secretion obtained at 28 degrees C, compared to that obtained at 37.5 degrees C, is weaker for strongly stimulating concentrations (3 g/1 and 5 g/1) than for a slightly stimulating concentration (1.5 g/1).