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[Changes, induced by certain flavonoids, of the hypotensive effects of arachidonic acid]
Comptes Rendus Des Seances De La Societe De Biologie Et De Ses Filiales
|January 1, 1977
Abstract:
In the rat, silybine and Z 12007, a derivative of rutoside, increase the vasodepressive activities of arachidonic acid, a prostaglandin precursor. They reduce the activity of PGE2. Quercetine also increases the hypotensive action of arachidonic acid. These three flavonoids are supposed to increase the prostaglandin biosynthesis.