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[A case of bronchial asthma whose disease activity was associated with changes in serum alkaline phosphatase
R Oosaki1, Y Mizushima, A Kawasaki
1First Department of Internal Medicine, Toyama Medical and Pharmaceutical University, Japan.
Nihon Kyobu Shikkan Gakkai Zasshi
|August 1, 1992
Abstract:
A 67-year-old female was admitted to our hospital with status asthmaticus. Serum alkaline phosphatase (ALP) level was elevated and ALP-linked immunoglobulins (ALP-Igs) were detected by ALP isozyme analysis. Treatment with prednisolone resulted in improvement of her asthmatic symptoms and serum ALP level. Thereafter, elevations of serum ALP and ALP-Igs levels were seen whenever she had an asthmatic attack. She had no manifestations of autoimmune diseases. Changes in ALP-Igs levels in association with asthmatic activity suggested that ALP-Igs were related to the pathogenesis of bronchial asthma in this case.