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Radiation-induced optic neuropathy: correlation of MR imaging and radiation dosimetry
W C Young1, A F Thornton, S S Gebarski
1Department of Radiology, University of Michigan Medical School, Ann Arbor.
Radiology
|December 1, 1992
Abstract:
The authors performed topographic correlation of dosimetric measurements with contrast medium-enhanced magnetic resonance (MR) imaging signal aberration in two cases of radiation optic neuropathy. The region of pathologic contrast enhancement in the optic nerve and chiasm had received 55-62 Gy, which supports the theory that the risk of injury to the optic nerve and chiasm increases steeply with radiation doses above the tolerance level of 50-55 Gy.