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Pathologic findings in pathologic myopia.

H E Grossniklaus1, W R Green

  • 1L. F. Montgomery Eye Pathology Laboratory, Emory Eye Center, Atlanta, Georgia.

Retina (Philadelphia, Pa.)
|January 1, 1992
PubMed
Summary
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Pathologic myopia involves optic nerve head changes and posterior staphyloma. Common findings include vitreous degeneration and retinal issues, with surgical eyes enucleated for various complications.

Area of Science:

  • Ophthalmology
  • Pathology

Background:

  • Pathologic myopia is a severe form of myopia.
  • Understanding its histopathologic features is crucial for patient management.

Purpose of the Study:

  • To analyze the histopathologic findings in eyes with pathologic myopia.
  • To correlate clinicopathologic findings with reasons for enucleation.

Main Methods:

  • Retrospective study of 308 eyes from 202 patients over 67 years.
  • Inclusion of both post-mortem and surgically enucleated eyes.
  • Analysis of histopathologic features and enucleation causes.

Main Results:

  • Most frequent findings: myopic optic nerve head (37.7%), posterior staphyloma (35.4%), vitreous degeneration (35.1%).

Related Experiment Videos

  • Other findings include retinal detachment (11.4%), subretinal neovascularization (5.2%), and Fuchs spot (3.2%).
  • Enucleation reasons: post-retinal detachment degeneration, secondary glaucoma, endophthalmitis.

    • Conclusions:

    • Pathologic myopia exhibits a spectrum of ocular changes.
    • Histopathology aids in understanding disease progression and complications.
    • Clinicopathologic correlation is vital for managing severe myopia.